Altered Effective Connectivity of Hippocampus-Dependent Episodic Memory Network in mTBI Survivors

Table 1

Functionally connected brain areas with the left hippocampus in normal controls and mTBI survivors (voxel level: , FDR corrected).

		⁢Normal controls					⁢mTBI					⁢mTBI versus normal controls
		Talairach					Talairach					Talairach
					value	voxels				value	voxels				value	voxels
Frontal cortex
Inferior frontal gyrus BA47
	L		−45	17	−11	5.00	37	−42	14	−11	5.74	82
R		24	8	−18	4.48	84	33	29	−12	8.25	123
Medial frontal gyrus BA10/11
	L		0	37	−12	4.35	20	0	49	−8	6.55	103
R		3	46	−10	4.09	18	3	49	−8	6.69	65
Temporal cortex
Inferior temporal gyrus BA21/20
	L		−50	−50	−10	6.08	72	−56	−9	−12	5.97	135
R							36	−2	−35	5.00	73
Middle temporal gyrus BA 21/22
	L		−50	2	−25	5.51	300	−36	1	−33	7.35	476
R		50	2	−18	4.00	20	53	5	−10	6.24	383
Fusiform gyrus BA20/37
	L		−36	−10	−22	5.56	167	−36	−13	−22	8.39	246
R							42	−44	−15	6.48	182
Parahippocampal gyrus
	L		−24	−12	−15	26.91	518	−21	−12	−15	23.79	628
R		27	−24	−9	8.75	193	24	−1	10	11.00	477
Hippocampus
R		30	−24	−9	7.14	130	36	−9	−12	10.72	183
Superior temporal gyrus BA38
	L		−30	10	−31	5.72	181	−33	−1	−13	8.76	255
R							27	4	−33	8.66	284
Superior temporal gyrus BA22/41
	L		−42	−27	−6	4.60	34	−53	−9	−10	7.13	439
R							48	−11	3	8.14	417	62	−40	13	8.18	51
Superior temporal gyrus BA39
	L							−45	−52	16	5.17	37
R							48	−52	11	6.62	39	48	−52	11	6.13	17
Parietal cortex
Supramarginal gyrus BA40
	L							−56	−49	19	4.60	13
R
Subcortical cortex
ACC
	L		−3	0	−8	5.93	40	−3	3	−3	4.34	41
R		3	32	−7	3.45	23	3	34	−9	4.00	79
PCC
	L		−18	−40	10	5.38	21	−15	−43	8	5.12	48
R							12	−34	18	4.24	28

BA: Brodmann area; ACC: anterior cingulate cortex; PCC: posterior cingulate cortex.