A Case-Control Study and Meta-Analysis Reveal BDNF Val66Met Is a Possible Risk Factor for PTSD

Table 5

Individual studies, their odds ratios, and 95% confidence intervals for recessive and dominant models on a genotype basis and on an allele model.

Study	Model	Odds ratios	95% CI
Zhang et al., 2006 [16]	Recessive	1.30	0.77; 2.17
	Dominant	0.25	0.03; 2.00
	Allele	0.74	0.47; 1.17
Lee et al., 2006 [30]	Recessive	0.83	0.48; 1.44
	Dominant	1.09	0.59; 2.00
	Allele	1.10	0.78; 1.56
Valente et al., 2011 [28]
All controls	Recessive	0.88	0.50; 1.57
	Dominant	1.71	0.38; 7.68
	Allele	1.15	0.69; 1.92
Controls only	Recessive	0.91	0.51; 1.61
	Dominant	1.63	0.36; 7.33
	Allele	1.13	0.68; 1.88
PTSD− only	Recessive	0.49	0.16; 1.46
	Dominant	0.08	0.02; 0.36
	Allele	2.16	0.77; 6.05
Lyoo et al., 2011 [31]	Recessive	0.79	0.29; 2.16
	Dominant	1.60	0.53; 3.88
	Allele	1.26	0.63; 2.55
Pivac et al., 2012 [22]	Recessive	0.91	0.65; 1.29
	Dominant	1.43	0.53; 3.87
	Allele	1.11	0.84; 1.47
Zhang et al., 2014 [27]	Recessive	0.39	0.20; 0.73
	Dominant	3.16	1.20; 8.33
	Allele	2.37	1.46; 3.86
Li et al., 2016 [23]	Recessive	0.77	0.50; 1.17
	Dominant	1.49	0.96;
	Allele	1.28	0.98;
Dretsch et al., 2016 [29]	Recessive	0.94	0.45; 1.94
	Dominant	3.53	1.06; 11.75
	Allele	1.37	0.76; 2.47
Our study	Recessive	0.94	0.55; 1.59
	Dominant	0.59	0.19; 1.79
	Allele	0.96	0.62; 1.50

Note. Significant findings are in bold; approaching significance.