Gender-Specific Hippocampal Dysrhythmia and Aberrant Hippocampal and Cortical Excitability in the APPswePS1dE9 Model of Alzheimer’s Disease

Figure 4

Frequency analysis in controls and APPswePS1dE9 mice. Using a FFT based approach, the mean EEG power [%] was calculated for males and females considering potential circadian rhythmicity (light/dark phase). For CA1 deflections, theta (4–8 Hz), gamma (30–50 Hz), and gamma (50–70 Hz) were quantified, for the cortical deflection delta (0.5–4 Hz) and beta (16–30 Hz). Frequency analysis was performed for all four ages (14, 15, 18, and 19 wks). . . .