Altered ERK1/2 Signaling in the Brain of Learned Helpless Rats: Relevance in Vulnerability to Developing Stress-Induced Depression

<div>mRNA levels of RSK1 and MSK2 in frontal cortex (FC) (a) and hippocampus (b) of tested controls (TC), non-learned helpless (non-LH), and learned helpless (LH) rats. Data are the mean ± SD from 6 rats in each group. Overall group differences in the 3 groups are as follows. 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Neural Plasticity

fig9

Figure 9

Figure 9: Altered ERK1/2 Signaling in the Brain of Learned Helpless Rats: Relevance in Vulnerability to Developing Stress-Induced Depression 