EEG Radiotelemetry in Small Laboratory Rodents: A Powerful State-of-the Art Approach in Neuropsychiatric, Neurodegenerative, and Epilepsy Research

Figure 5

Auditory research using EEG radiotelemetry. Implantable EEG radiotelemetry can be used to record auditory evoked potentials. As depicted in (a), the TDT stimulation unit is connected to a loudspeaker and via an oscilloscope to an A/D converter. The data exchange matrix does not only receive EEG data via the receiver plate but also receive a trigger signal from the A/D converter that is integrated into the EEG recording. (b) Auditory setup with loudspeaker inside a sound isolation chamber. The radiofrequency transmitter implanted mouse is placed on the receiver plate inside the chamber. (c) Scheme of the paired click paradigm protocol. As illustrated in (d), EEG channels are synchronized with the double click trigger signal (S1, S2) enabling complex averaging processes for subsequent studies of auditory evoked potentials.

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