Review Article

Expression and Function of the Endocannabinoid System in the Retina and the Visual Brain

Table 2

Cannabinoid receptor type 1 protein distribution in the adult retina of various species.

Retinal cells

PhotoreceptorsExpression in the inner [17, 56] and outer segments [22]
Strong labeling in the cone pedicles [17, 51, 53, 56, 78]

Horizontal cellsExpression in the membrane but not in dendrites [17, 51, 56]

Bipolar cellsExpression in the dendrites, cell body, and axons of rod bipolar cells [17, 51]

Amacrine cellsExpression in amacrine cells, including GABAergic amacrine cells [17, 51, 56, 65]

Inner plexiform layerUnspecified expression in the IPL [17, 22, 53]
Expression in the synapses of rod bipolar cells [51]
Higher expression in the synapses of ON cone bipolar cells compared to OFF cone bipolar cells [78]

Ganglion cellsExpression in the cell body and fibers [17, 22, 53, 56, 83]

Müller cellsAbsence of expression [17, 53, 56]
Expression in the goldfish retina only [78]