MRI Biomarkers for Hand-Motor Outcome Prediction and Therapy Monitoring following Stroke

Figure 3

Task characteristics have a crucial impact on fMRI results. Unilateral hand and finger movements performed with left and right hand in a group of 15 right-handed young participants (group results for the premeasurement of the training paradigm reported in [12]). Whereas the fist clenching task shows high lateralization in the cortical and cerebellar representation sites, unilateral finger sequence movements are bilaterally represented. In addition, finger sequences involve basal ganglia and inferior cerebellar hemisphere, at least when performed with the nondominant left hand.