State and Training Effects of Mindfulness Meditation on Brain Networks Reflect Neuronal Mechanisms of Its Antidepressant Effect

Table 3

Regions showing functional differences between conditions (rest versus meditation).

Analysis	Rest > meditation					Meditation > rest
	Region	Side		MNI coordinates	-score	Region	Side		MNI coordinates	-score
ICA	(, FWE-corrected cluster threshold at )
	dACC	R	202	9 21 36	5.70	Precuneus	R	178	3 −66 27	4.94
	sgACC	R	349	9 27 0	5.60	TPJ/IPL	L	157	−51 −57 27	4.31
	AI	L	336	−39 9 0	5.02
	AI	R	37	45 18 0	4.34
	IFG/BA9	R	21	60 18 27	4.26
Seed-based FC	(, FWE-corrected cluster threshold at )
(ROI: pgACC)	IPL	L	42	−45 −39 36	4.31	TPJ	R	58	57 −66 36	4.51
	IPL	R	45	39 −51 51	4.17	MPFC	R	36	9 51 9	4.49
						STG	L	23	−42 −60 18	3.86
(ROI: dACC)	AI	L	20	−36 18 3	4.2	n.s.
ReHo	(, FWE-corrected cluster threshold at )
	n.s.					dACC	R	125	0 36 15	5.32
						MPFC	R	125	6 48 12	4.24
						Putamen	L	77	−21 6 3	4.40

Notes: AI, anterior insula; dACC, dorsal anterior cingulate cortex; IPL, inferior parietal lobe; K, cluster size; MPFC, medial prefrontal cortex; pgACC, pregenual anterior cingulate cortex; sgACC, subgenual anterior cingulate cortex; STG, superior temporal gyrus; TPJ, temporoparietal junction; and BA: brodmann area.
Family-wise error.
A combined threshold of and a minimum cluster size determined by AlphaSim algorithm in AFNI, resulting in FWE-corrected threshold of . An estimate of the spatial correlation across voxels was modeled using the program 3dFWHM in AFNI.
AlphaSim: http://afni.nimh.nih.gov/pub/dist/doc/manual/AlphaSim.pdf.
3dFWHM: http://afni.nimh.nih.gov/pub/dist/doc/program_help/3dFWHM.html.