Correlations between the Memory-Related Behavior and the Level of Oxidative Stress Biomarkers in the Mice Brain, Provoked by an Acute Administration of CB Receptor Ligands

Figure 2

Effects of acute pretraining (a) or posttraining (b) CB1/CB2 receptor agonist WIN 55,212-2 or saline administration on the latency index (LI) in the PA test in mice. WIN 55,212-2 (0.25, 0.5, and 1.0 mg/kg; ip) or vehicle was administered 30 min before the first trial (a) or immediately after the first trial (b) and the mice were retested 24 h later; ; the means ± SEM; versus vehicle-treated control group; Tukey’s test.

(a)

(b)