CB2 Cannabinoid Receptor Knockout in Mice Impairs Contextual Long-Term Memory and Enhances Spatial Working Memory
Spatial working memory of CB2R KO mice is enhanced when assessed with a spontaneous alternation test in a Y-maze. (a) Representative tracking of mouse movement for 3 min in a Y-maze. Consecutive entries into three different arms were counted as an alternation. (b) KO mice displayed a higher rate of spontaneous alternation compared with WT mice. , -test. (c) The total number of arm entries was not significantly different between the two strains. Error bars represent SEM.