Impaired Hippocampal Glutamate and Glutamine Metabolism in the db/db Mouse Model of Type 2 Diabetes Mellitus

Figure 4

¹³C labeling from [U-¹³C]glutamate metabolism of cerebral cortical and hippocampal slices of control and db/db mice. TCA cycle intermediates and amino acids labeled from [U-¹³C]glutamate metabolism during incubations of cerebral cortical (a) and hippocampal (b) slices of control and db/db mice. Results are presented as means ± SEM, , Student’s t-test, .

(a)

(b)