Treadmill Exercise Improves Motor Dysfunction and Hyperactivity of the Corticostriatal Glutamatergic Pathway in Rats with 6-OHDA-Induced Parkinson’s Disease

Figure 8

Effect of treadmill exercise on evoked electrical activity of striatal neurons in the rat model of Parkinson’s disease. (a) The thresholds for evoking striatal neuron responses in rats. (b) Changes in average firing rates in striatal neurons after cortical stimulation. Analysis of spontaneous firing patterns in striatal neurons. (c) Change ratio of striatal neuron firing rates after stimulation. (d) The interval time of striatal neurons response after cortical stimulation. (a, c, d) Compared to the control groups, . Compared to the PD groups, ^# and ^##. (b) Compared to before cortical stimulation, . Compare to the control groups, ^##. Compared to the PD groups, ^※※. Control: control group; control + Ex: control plus exercise group; PD: Parkinson’s disease group; PD + Ex: Parkinson’s disease plus exercise group.

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