Distinct Pattern of Microgliosis in the Olfactory Bulb of Neurodegenerative Proteinopathies

Figure 1

Overview of the human olfactory bulb (OB) analyzed in the study: (a) Nissl staining of the human olfactory bulb showing the glomerular layer (GLOM), the granular cell layer (GCL), and the olfactory tract (OT). Inserts: (b) higher magnification of the most rostral portion of an OB depicting the distribution of Nissl stained cells in the GLOM and the GCL. (c) The GLOM was further identified by staining for tyrosine hydroxylase (TH) expressing neurons within glomeruli, counterstained with hematoxylin. OB tissue from control case, scale bars represent 500 μm in (a) and 50 μm in inserts (b, c).