White Matter Hyperintensity Load Modulates Brain Morphometry and Brain Connectivity in Healthy Adults: A Neuroplastic Mechanism?

Figure 2

An example of the output from the Lesion Segmentation Tool for the quantification of WMHs. An overview is given in the glass-brain template shown in the upper half. A single slice is instead reproduced in the lower half, showing mainly periventricular, but also some sparse deep WMHs. This specific participant is a 70-year-old man with a raw WMH volume of 3.25 ml, equal to 0.21% of his intracranial volume.