Research Article
Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice
Figure 3
Elevated cortex glutamate level of SNAP-25 cKO mice. (a) The concentration of glutamate (μg/mL) in the microdialysis fluid (Ctrls, ; cKOs, ). (b) The concentration of amino acid neurotransmitters (×106 pg/mL) in brain homogenates ( per group). (c) The original representative HPLC figures of different genotypic mice. compared with control littermates. Asp: aspartate; Glu: glutamate; Asn: asparaginate; Gln: glutamine; Gly: glycine; GABA: γ-aminobutyric acid.
(a) |
(b) |
(c) |