|
| First author | Title | Year | Journal |
|
| | Evidences supporting α-synuclein spreading | | |
| Braak | “Staging of Brain Pathology Related to Sporadic Parkinson’s Disease” | 2003 | Neurobiol. Aging |
| Del Tredici | “Sporadic Parkinson’s Disease: Development and Distribution of Alpha-Synuclein Pathology” | 2016 | Neuropathol. Appl. Neurobiol. |
| Iljina | “Kinetic Model of the Aggregation of Alpha-Synuclein Provides Insights into Prion-Like Spreading” | 2016 | Proc. Natl. Acad. Sci. USA |
| Oh | “Mesenchymal Stem Cells Inhibit Transmission of α-Synuclein by Modulating Clathrin-Mediated Endocytosis in a Parkinsonian Model” | 2016 | Cell Rep. |
| Helwig | “Brain Propagation of Transduced Alpha-Synuclein Involves Non-Fibrillar Protein Species and Is Enhanced in Alpha-Synuclein Null Mice” | 2016 | Brain |
| Bernis | “Prion-Like Propagation of Human Brain-Derived Alpha-Synuclein in Transgenic Mice Expressing Human Wild-Type Alpha-Synuclein” | 2015 | Acta Neuropathol. Commun. |
| Illes-Toth | “Distinct Higher-Order Alpha-Synuclein Oligomers Induce Intracellular Aggregation” | 2015 | Biochem. J. |
| Ulusoy | “Neuron-to-Neuron α-Synuclein Propagation In Vivo Is Independent of Neuronal Injury” | 2015 | Acta Neuropathol. Commun. |
| Stuendl | “Induction of α-Synuclein Aggregate Formation by CSF Exosomes from Patients with Parkinson’s Disease and Dementia with Lewy Bodies” | 2016 | Brain |
| Prusiner | “Evidence for α-Synuclein Prions Causing Multiple System Atrophy in Humans with Parkinsonism” | 2015 | Proc. Natl. Acad. Sci. USA |
| Masuda-Suzukake | “Pathological Alpha-Synuclein Propagates through Neural Networks” | 2014 | Acta Neuropathol. Commun. |
| Sacino | “Brain Injection of Alpha-Synuclein Induces Multiple Proteinopathies, Gliosis, and a Neuronal Injury Marker” | 2014 | J. Neurosci. |
| Kovacs | “Intracellular Processing of Disease-Associated α-Synuclein in the Human Brain Suggests Prion-Like Cell-to-Cell Spread” | 2014 | Neurobiol. Dis. |
| Recasens | “Lewy Body Extracts from Parkinson Disease Brains Trigger α-Synuclein Pathology and Neurodegeneration in Mice and Monkeys” | 2014 | Ann. Neurol. |
| Ulusoy | “Caudo-Rostral Brain Spreading of α-Synuclein through Vagal Connections” | 2013 | EMBO Mol. Med. |
| Masuda-Suzukake | “Prion-Like Spreading of Pathological α-Synuclein in Brain” | 2013 | Brain |
| Angot | “Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo” | 2012 | PLoS One |
| Luk | “Intracerebral Inoculation of Pathological Alpha-Synuclein Initiates a Rapidly Progressive Neurodegenerative Alpha-Synucleinopathy in Mice” | 2012 | J. Exp. Med. |
| Luk | “Pathological Alpha-Synuclein Transmission Initiates Parkinson-Like Neurodegeneration in Nontransgenic Mice” | 2012 | Science |
| Kordower | “Transfer of Host-Derived Alpha Synuclein to Grafted Dopaminergic Neurons in Rat” | 2011 | Neurobiol. Dis. |
| Hansen | “Alpha-Synuclein Propagates from Mouse Brain to Grafted Dopaminergic Neurons and Seeds Aggregation in Cultured Human Cells” | 2011 | J. Clin. Invest. |
| Danzer | “Seeding Induced by Alpha-Synuclein Oligomers Provides Evidence for Spreading of Alpha-Synuclein Pathology” | 2009 | J. Neurochem. |
| Kordower | “Transplanted Dopaminergic Neurons Develop PD Pathologic Changes: A Second Case Report” | 2008 | Mov. Disord. |
| Kordower | “Lewy Body-Like Pathology in Long-Term Embryonic Nigral Transplants in Parkinson’s Disease” | 2008 | Nat. Med. |
| Li | “Lewy Bodies in Grafted Neurons in Subjects with Parkinson’s Disease Suggest Host-to-Graft Disease Propagation” | 2008 | Nat. Med. |
|
| | Evidences confuting α-synuclein spreading | | |
| Sumikura | “Distribution of Alpha-Synuclein in the Spinal Cord and Dorsal Root Ganglia in an Autopsy Cohort of Elderly Persons” | 2015 | Acta Neuropathol. Commun. |
| Sacino | “Amyloidogenic α-Synuclein Seeds Do Not Invariably Induce Rapid, Widespread Pathology in Mice” | 2014 | Acta Neuropathol. |
| Halliday | “The Progression of Pathology in Parkinson’s Disease” | 2010 | Ann. N. Y. Acad. Sci. |
| Jang | “Non-Classical Exocytosis of Alpha-Synuclein Is Sensitive to Folding States and Promoted under Stress Conditions” | 2010 | J. Neurochem. |
| Hawkes | “Parkinson’s Disease and Aging: Same or Different Process?” | 2008 | Mov. Disord. |
| Kalaitzakis | “Controversies over the Staging of Alpha-Synuclein Pathology in Parkinson’s Disease” | 2008 | Acta Neuropathol. |
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