Research Article

Regionally Specific Regulation of Sensorimotor Network Connectivity Following Tactile Improvement

Table 2

Anatomical location, size, T-value, and peak coordinates (in MNI space) for whole-brain multiple regressions of the resting-state sensorimotor network with 2ptD thresholds or 2ptD gain as covariate of interest. Clusters are reported at whole brain (k > 10 vx). Voxels are reported as 2 × 2 × 2 mm3.

−TPDbaselineTPDbaseline
LocationBAVoxelT-valuexyzPFWELocationBAVoxelT-valuexyzPFWE
L frontal pole10184.62−246416L precentral gyrus6186.22−38−448
L angular gyrus355.86−34−6240
L calcarine gyrus17385.52−6−100−4
L parahippocampal gyrus165.04−14−14−18
L precuneus104.88−6−5866
R temporal pole38113.395216−10
R rolandic operculum22133.376446

−TPDpostTPDpost
LocationBAVoxelT-valuexyzPFWELocationBAVoxelT-valuexyzPFWE
L postcentral gyrus4695.84−58−12300.039L parahippocampal gyrus145.85−30−30−16
L cerebellum (VI)165.13−32−44−28L inferior temporal gyrus38, 21485.74−424−34
R calcarine gyrus194.8714−6016L medial temporal gyrus38235.45−2412−30
L inferior temporal gyrus124.78−56−58−24R precentral gyrus6105.4134−1464
R superior frontal gyrus8295.41182246
R superior orbital gyrus47165.141818−12
L inferior frontal gyrus46, 10294.96−424020
R medial cingulate cortex32124.93141040
L calcarine gyrus144.92−10−866
R medial temporal gyrus21144.8664−26−14
L putamen114.58−30−1010
L inferior frontal gyrus46144.52−423222
L parahippocampal gyrus104.27−14−14−28

−TPDgainTPDgain
LocationBAvoxelT-valuexyzPFWELocationBAvoxelT-valuexyzPFWE
R cerebellum (IV, V)217.0118−50−22L medial frontal gyrus11135.84−4452−14
R superior medial gyrus246.92105040L medial frontal gyrus135.74−421250
L medial occipital gyrus19, 39215.05−46−8420R hippocampus125.2732−18−120.040
R supramarginal gyrus194.7342−3636L precuneus7265.09−6−5448
L fusiform gyrus19154.72−32−48−10L postcentral gyrus4104.96−62−1240
L medial temporal gyrus22154.13−58−324

Small volume corrected on cluster level. BA: Brodmann area; L: left; R: right.