Localizing Age-Related Changes in Brain Structure Using Voxel-Based Morphometry

Figure 1

Late childhood minus early adolescence statistical parametric mapping. Traditionally presented z-score map (height threshold, 0.05; extent threshold, 50) for the gray matter voxel reductions observed between late childhood and early adolescence (upper). Voxels showing significant changes in gray matter mapped onto a normalized structural image in the axial plane (lower).