Maturation, Refinement, and Serotonergic Modulation of Cerebellar Cortical Circuits in Normal Development and in Murine Models of Autism

Table 1

	Tsc1^PC	Pten^PC	Shank2^PC Peter et al. [158]	Shank2^PC Ha et al. [165]
Structural features
Soma	Normal	Hypertrophic	Normal
Dendrites	n.a.	Hypertrophic	Normal
Spines	Increased	n.a.	Normal
Axon	Varicosities	Varicosities	n.a.
Functional features
spont. firing	Decreased	Decreased	Normal frequency, increased irregularity	n.a.
Excitability	Decreased	Decreased	n.a.	n.a.
spont. EPSCs	n.a.	n.a.	n.a.	Decreased frequency
PF-EPSCs	Normal	Hyperfunctional	Normal	n.a.
PF-LTD	n.a.	n.a.	n.a. (but normal in the global KO)	Normal
CF-EPSCs	Normal	Hypofunctional	Normal	n.a.
GABAergic IPSCs	Normal	n.a.	n.a. (increased IPSC frequency in the global KO)	n.a.