Research Article

Spinal Excitability Changes after Transspinal and Transcortical Paired Associative Stimulation in Humans

Table 2

TEPs sigmoid function parameters before and after transspinal-transcortical PAS.

R-TAL-TAR-MGL-MGR-SOLL-SOLR-PLL-PL
BeforeAfterBeforeAfterBeforeAfterBeforeAfterBeforeAfterBeforeAfterBeforeAfterBeforeAfter

Max amplitude97.76 ± 0.7573.87 ± 4.66101.21 ± 2.8975.19 ± 5.5296.60 ± 1.6390.86 ± 7.7199.63 ± 2.39121.90 ± 22.994.79 ± 1.2482.60 ± 4.1298.60 ± 1.7077.16 ± 6.7696.67 ± 2.4870.04 ± 5.7997.32 ± 1.6283.83 ± 7.40
m0.18 ± 0.020.17 ± 0.020.20 ± 0.070.29 ± 0.150.23 ± 0.040.21 ± 0.040.24 ± 0.050.17 ± 0.010.23 ± 0.030.20 ± 0.030.20 ± 0.030.19 ± 0.030.20 ± 0.020.17 ± 0.020.17 ± 0.020.15 ± 0.02
Slope12.97 ± 1.4613.44 ± 1.4315.79 ± 2.2214.38 ± 2.3111.33 ± 1.6512.42 ± 1.6911.12 ± 1.4212.96 ± 3.4210.06 ± 1.3111.70 ± 1.3812.17 ± 1.5113.24 ± 1.8112.24 ± 1.8713.89 ± 1.5313.62 ± 1.4517.63 ± 2.70
Stimulus threshold42.41 ± 4.3040.19 ± 4.5844.33 ± 2.9642.65 ± 4.1144.87 ± 5.2943.19 ± 5.0348.31 ± 3.0446.49 ± 3.1344.13 ± 4.4843.31 ± 4.7546.43 ± 3.1145.98 ± 3.0943.80 ± 4.4242.46 ± 4.8145.33 ± 3.5743.31 ± 3.87
Stimulus 50% max55.38 ± 4.8053.63 ± 5.3560.12 ± 4.0657.04 ± 4.1156.20 ± 6.0055.61 ± 6.3159.44 ± 3.8959.45 ± 3.8254.20 ± 4.9955.01 ± 5.1058.60 ± 4.4159.22 ± 4.2956.04 ± 5.4056.34 ± 5.2258.95 ± 4.2760.94 ± 4.75
Stimulus max68.35 ± 5.6567.07 ± 6.3675.90 ± 5.8471.42 ± 5.2567.53 ± 7.0468.02 ± 7.7570.56 ± 5.0072.41 ± 4.6264.26 ± 5.7666.70 ± 5.7770.76 ± 5.8072.46 ± 5.8168.28 ± 6.7670.23 ± 6.0172.57 ± 5.2878.57 ± 6.68

Results of predicted parameters from the sigmoid input-output relation of TEPs recorded at all points of the recruitment curve. TEPs were normalized to the homonymous maximal TEP recorded before PAS and were plotted against real stimulation intensities. This was performed separately for each subject, and averages were estimated and grouped based on time. m: slope parameter of the function. Mean ± SE. TA: tibialis anterior; MG: medial gastrocnemius; SOL: soleus; PL: peroneus longus; R: right; L: left. Italics indicate statistically significant differences before and after PAS.