Research Article

Long-Term High Salt Intake Involves Reduced SK Currents and Increased Excitability of PVN Neurons with Projections to the Rostral Ventrolateral Medulla in Rats

Table 1

Properties of PVN-RVLM neurons.

GroupnVm (mV)Cm (pF)Rinput (GΩ)Vt (mV)

NS6−57.8 ± 3.251.2 ± 4.70.54 ± 0.03−42.8 ± 2.8
NS apamin5−55.8 ± 1.744.8 ± 3.30.78 ± 0.11−38.0 ± 1.3
HS6−59.3 ± 1.547.0 ± 4.30.83 ± 0.08−40.4 ± 1.8
HS apamin6−58.0 ± 1.041.2 ± 2.40.96 ± 0.11−41.0 ± 2.1

Vm: resting membrane potential; Cm: membrane capacitance; Rinput: depolarizing input resistance; Vt: subthreshold of membrane potential to fire action potential.