Research Article

Study on Lesion Assessment of Cerebello-Thalamo-Cortical Network in Wilson’s Disease with Diffusion Tensor Imaging

Table 1

Details of demographic and clinical features of patients with WD.

At initial presentationPatients of WDControls

Patients (number)3530
Males/females (number)21/1415/15
Ages (years, mean ± SD)26.94 ± 6.9826.2 ± 5.62
Duration of illness (months, mean ± SD)93.9 ± 60.5
Family history23%
KF ring present100%
Extrapyramidal signs100%
Modified Goldstein classificationII~IV
24 h urinary excretion of copper (μmmol/L)873.3 ± 538.8
Copper-dependent oxidase activity (L)0.04 ± 0.06