Corticospinal Plasticity in Bilateral Primary Motor Cortices Induced by Paired Associative Stimulation to the Dominant Hemisphere Does Not Differ between Young and Older Adults

Figure 4

Average MEP change in young and older LTP- and LTD-like responders in the attend right condition. MEP amplitudes increased significantly in LTP-like responders and decreased significantly in LTD-like responders. Although there was no difference in the corticospinal plasticity induced in the target and nontarget motor cortices in LTP-like responders, there was a significant difference between the hemispheres in LTD-like responders. PAS-induced corticospinal plasticity was significant (different from zero) only in the target (stimulated) pathway in both LTP- and LTD-like responders. Error bars denote SEM.

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