Altered Brain Functional Activity in Infants with Congenital Bilateral Severe Sensorineural Hearing Loss: A Resting-State Functional MRI Study under Sedation

Figure 2

Group analysis of ReHo between infants with CSSHL and healthy controls. Compared with control group, decreased (red) ReHo was observed in left superior temporal gyrus (BA22) (, ES = 0.86), left inferior frontal gyrus (BA45) (, ES = 1.00), left inferior prefrontal gyrus (BA47) (, ES = 1.10), left dorsolateral prefrontal cortex (BA46) (, ES = 0.91), left medial frontal gyrus (BA32) (, ES = 1.03), and left temporal polar gyrus (BA38) (, ES = 0.88). Increased (blue) ReHo was observed in left occipital lobe which included BA18 (, ES = −0.91), BA19 (, ES = −1.20), and BA17 (, ES = −1.41). AlphaSim corrected (, cluster size > 228 voxels). The significance level of activity was indicated by the color bar (T), increasing as red proceeding to yellow decreasing as blue to cyan.