Research Article

Altered Brain Functional Activity in Infants with Congenital Bilateral Severe Sensorineural Hearing Loss: A Resting-State Functional MRI Study under Sedation

Table 2

Comparison of ReHo differences between infants with CSSHL and hearing controls.

RegionHBAVolume (mm3)CoordinatesPeakES
-value

Deaf < control
 Superior temporal gyrusL2214−56−1732.650.86
 Inferior frontal gyrusL4519−44−30103.081.00
 Inferior prefrontal gyrusL4774−4238−23.401.10
 Dorsolateral prefrontal gyrusL4618−3651172.820.91
 Medial frontal gyrusL3245−114593.171.03
 Temporal poleL3852−3018−312.700.88

Deaf > control
 Occipital gyrusR18243−7−661−2.81−0.91
 Occipital gyrusR19195−8−8727−3.71−1.20
 Medial occipital gyrusR1733−2−974−4.35−1.41

CSSHL: congenital severe sensorineural hearing loss; H, hemisphere; L, left; R, right; B, bilateral; BA, Brodmann’s area. AlphaSim corrected ( < 0.05, voxel-level cut-off); ES, value of Cohen was used to describe the effect size. Indicating the significant difference compared with controls.