Research Article

Thalamocortical Connectivity and Microstructural Changes in Congenital and Late Blindness

Table 1

Overview of the cortical target masks and the corresponding thalamic nuclei.

Target maskCortical labelsCorresponding thalamic nuclei

OccipitalPericalcarine
Cuneus
Lateral occipital
Lingual
Pulvinar
LGN
MGN
Lateral nucleus

TemporalMiddle temporal
Inferior temporal
Superior temporal
Transverse temporal
Fusiform
Temporal pole
Banks of superior temporal sulcus
Entorhinal
Parahippocampal
Pulvinar
MGN

Somatosensory/parietal-postcentralPostcentral
Supramarginal
Superior parietal
Inferior parietal
Precuneus
Isthmus cingulate
Posterior cingulate
Lateral nucleus
Ventrolateral nucleus
Ventroposterior nucleus

Motor/precentralPrecentral
Caudal middle frontal
Paracentral
Ventrolateral nucleus
Ventroanterior nucleus

FrontalSuperior frontal
Frontal pole
Medial orbitofrontal
Lateral orbitofrontal
Rostral middle frontal
Rostral anterior cingulate
Pars opercularis
Pars orbitalis
Pars triangularis
Anterior nucleus
Mediodorsal nucleus

Cortical target masks defined by combining labels given by the Desikan-Killiany atlas. The last column shows the thalamic nuclei, corresponding to the respective cortical projection sites as defined from an anatomical atlas based on the normal healthy human brain [5]. LGN: lateral geniculate nuclei; MGN: medial geniculate nuclei.