Thalamocortical Connectivity and Microstructural Changes in Congenital and Late Blindness

Table 3

Mean and standard deviations of FA and MD within the five thalamic white matter projections.

		Occipital			Temporal			Sensory			Motor			Frontal
		CB	LB	NS	CB	LB	NS	CB	LB	NS	CB	LB	NS	CB	LB	NS
FA; Mean; (SD)	L	0.46	0.45	0.53	0.36	0.35	0.40	0.45	0.44	0.45	0.47	0.43	0.44	0.41	0.41	0.41
		(0.05)	(0.05)	(0.03)	(0.05)	(0.04)	(0.02)	(0.05)	(0.03)	(0.04)	(0.04)	(0.05)	(0.05)	(0.05)	(0.03)	(0.04)
	R	0.43	0.42	0.51	0.35	0.34	0.39	0.44	0.44	0.44	0.46	0.44	0.46	0.40	0.38	0.40
		(0.05)	(0.04)	(0.03)	(0.04)	(0.04)	(0.03)	(0.04)	(0.03)	(0.04)	(0.03)	(0.03)	(0.04)	(0.04)	(0.03)	(0.03)
MD; Mean; (SD)	L	0.67	0.72	0.65	0.71	0.72	0.67	0.64	0.64	0.64	0.63	0.65	0.65	0.62	0.62	0.62
		(0.04)	(0.09)	(0.04)	(0.04)	(0.07)	(0.04)	(0.04)	(0.05)	(0.06)	(0.06)	(0.08)	(0.09)	(0.04)	(0.05)	(0.03)
	R	0.70	0.71	0.64	0.71	0.72	0.67	0.62	0.62	0.62	0.61	0.62	0.61	0.64	0.65	0.64
		(0.05)	(0.09)	(0.03)	(0.04)	(0.06)	(0.04)	(0.03)	(0.04)	(0.04)	(0.04)	(0.05)	(0.04)	(0.04)	(0.05)	(0.02)

Significantly reduced FA in CB and LB and increased MD in LB compared to NS at or , Bonferroni corrected. CB: congenitally blind; LB: late blind; NS: normal sighted controls; L: left; R: right; FA: fractional anisotropy; MD: mean diffusivity, values × 10⁻³; SD: standard deviation.