Consumption of a High-Fat Diet Alters Perineuronal Nets in the Prefrontal Cortex

Figure 1

Dietary manipulation. (a) Experimental timeline. Animals were fed with one of three dietary conditions for 21 days, and then tissues were immediately extracted and analyzed. (b) Percent weight gain from baseline in chow (white), HF-CM (gray), and HF-AL (black) groups. (c) Approximate body fat accumulation, expressed as the weight of the right epididymal fat pad over the length of the right ulna bone. (d) Caloric intake across the dietary manipulation. (e) Food consumption expressed as the ratio of kilocalories consumed to body weight. Values represent the mean ± SEM ().

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