Research Article
Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling
Table 1
Statistical analysis of the effects produced by D3R antagonists, by MEK-ERK and PI3K-mTOR inhibitors, and by BDNF-TrkB signaling inhibitors on ropinirole-induced structural plasticity in F3 DA neurons.
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1DA antagonists: sulpiride, SB277011-A, S33084, and SCH23390. 2mTOR inhibitors: PD98059, LY294002, and rapamycin. 3TrkB inhibitors: α-BDNF, TrkB-Fc Chimera, K252a, and PP2. The original values represented as mean ± SEM can be found in Figure 4. Two way ANOVA: ; ; and . |