Cholinergic Mechanisms of Target Oddball Stimuli Detection: The Late “P300-Like” Event-Related Potential in Rats

Figure 1

Schematic presentation of different phases of the active oddball discriminant task. Animals had to correctly respond to infrequent target (oddball) tones whilst correctly ignoring frequent standard tones. The criteria for good behavioral performance was >80% response to target and <20% response to standard tones. Epidural electrodes implanted in the rats recorded continuous EEG from specific brain areas (frontal, parietal, and occipital).