Research Article

Newly Generated Cells in the Dentate Gyrus Differentially Respond to Brief Spatial Exploration and Forced Swim in Adult Female Balb/C Mice

Figure 4

Neuronal activation in the dentate gyrus of adult mice after forced-swim exposure. (a) Experimental design. Female Balb/C mice kept under standard housing conditions were exposed to forced-swim stress (FS) for 5 minutes as described in Materials and Methods. (b) Representative micrographs of Arc-labelled cells in mice exposed to forced-swim are shown. The scale bar in B is equal to 100 μm. Insets correspond to high-power images of Arc-positive cells. The scale bar in the insets is equal to 20 μm. (c) Quantification of Arc-labelled cells showed more in the FS group than in the No-FS group. Asterisk indicate . Data are expressed as the of the absolute number of Arc-cells, and comparisons in (c) were performed with unpaired Student’s -test. per group.
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