Electroacupuncture Treatment Alleviates the Remifentanil-Induced Hyperalgesia by Regulating the Activities of the Ventral Posterior Lateral Nucleus of the Thalamus Neurons in Rats

Figure 4

Effects of RF infusion on spontaneous neuronal activity in VPL neurons. (a) Representative spontaneous activity of VPL neurons before and after RF infusion in the vehicle- and RF-treated rats. Upper: representative traces of the neuronal discharges. Scale bar: 400 μV, 10 sec. Middle: scatter plot of the spikes. Lower: histograms show the number of action potentials (spikes) per second (bin width, 2 seconds). (b) Cluster plots depicting activity of VPL neurons (rows) before and after RF infusion in the two groups are shown. Warm and cool colors indicate the increase and decrease, respectively, in the spikes of multichannel recorded neurons. (c) Averaged spontaneous activity of VPL neurons (spikes per second) before and after RF infusion in vehicle- and RF-treated rats. versus the corresponding vehicle group, two-way ANOVA followed by the Bonferroni post hoc test, to 30 cells (four to six rats) per group.

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