Neural Plasticity

Research Article

Impact of Global Mean Normalization on Regional Glucose Metabolism in the Human Brain

Table 1

Details of different groups imaged at the various sites (Germany, USA, Denmark, and Belgium; see text for details).


PET imaging site	Experimental group	Control group

Site number 1, Germany (Technical University of Munich)	HAEO ()	HAEC_GER ()

Site number 2, USA (University of California, Irvine)	Sev0.25% ()	^∗ HAEC_sev ()
	Sev0.5% ()
	Des1% ()	HAEC_des ()

Site number 3, Denmark (Rigshospitalet, Copenhagen University Hospital)	CB ()	HAEC_DEN ()

Site number 4, Belgium (University Hospital of Liege)	UWS ()	HAEC_BEL ()
	MCS ()
	EMCS ()

indicates that both absolute CMR_glc (aCMR_glc) and quantified CMR_glc (qCMR_glc) were obtained from the USA site, enabling comparison between them (see Figures 1(b) and 1(c)). aCMR_glc: absolute CMR_glc with blood sampling of the tracer FDG supply to the brain; qCMR_glc: calibration of quantified comparing qCMR_glc with aCMR_glc for HAEC only eqs. (1 and 2); HAEC: healthy people awake with eyes closed (control condition); HAEO: healthy people awake with eyes open; Des1%: healthy people sedated with 1% desflurane; Sev0.25%: healthy people sedated with 0.25% sevoflurane; Sev0.50%: healthy people sedated with 0.5% sevoflurane; CB: awake people with congenital blindness; UWS: patients who were unresponsive wakefulness syndrome; MCS: patients who were in a minimally conscious state; EMCS: patients who emerged from MCS.