Reorganization of the Action Observation Network and Sensory-Motor System in Children with Unilateral Cerebral Palsy: An fMRI Study
Table 2
Areas elicited by observation of all object-related hand actions versus BASELINE condition in UCP children and age-matched TD children [5].
Area name
BA
UCP children
TD children
Talairach’s coordinates
Cluster size
-value
Talairach’s coordinates
Cluster size
-value
Inferior temporal gyrus
37
DS
−44
−65
0
8307
18.4
−44
−64
0
15,536
20.6
Non-DS
47
−61
−2
8369
15.6
44
−61
1
18,659
18.7
Superior temporal gyrus
22
DS
−48
−35
12
1357
10.4
−51
−40
11
1531
8.2
Non-DS
53
−33
9
1534
8.6
50
−40
11
2584
9.2
Inferior parietal lobule
40
DS
−44
−40
39
4278
7.6
−56
−31
30
3751
9.9
Non-DS
48
−36
36
2281
7.7
57
−31
27
1669
6.9
Anterior IPS
40-7
DS
−36
−45
45
4231
12.7
−32
−44
50
4806
15.4
Non-DS
37
−50
48
3023
7.3
33
−45
49
2265
10.6
Superior parietal lobule
7
DS
−16
−66
45
5112
11.9
−25
−67
46
11,593
15.7
Non-DS
22
−62
45
3212
8.0
23
−64
47
8594
11.7
Precentral gyrus
6-4
DS
−35
−11
51
1688
6.2
−33
−16
52
3292
7.9
Non-DS
35
−9
53
1458
7.2
32
−14
52
1865
5.3
6-9
DS
−40
4
38
1260
8.3
−47
−2
32
2019
9.5
Non-DS
43
6
39
1808
7.1
43
2
34
3242
9.7
Middle-superior frontal gyrus
9-10-46
DS
−50
14
24
925
5.0
−39
38
22
1180
5.0
Non-DS
41
23
17
899
7.2
43
17
21
1154
5.1
Inferior frontal gyrus
45–47
DS
−33
23
2
441
5.2
Non-DS
45
32
5
982
5.1
41
23
3
538
6.2
Middle occipital gyrus
18
DS
−23
−85
4
1465
10.3
−22
−83
3
3897
11.6
Non-DS
22
−84
7
1417
7.4
24
−83
2
1369
14.9
BA = Brodmann area; UCP = unilateral cerebral palsy; TD = typically developing; DS = dominant side (controlateral to dominant hand); non-DS = nondominant side (controlateral to nondominant hand); IPS=inferior parietal sulcus. For convention, the dominant hand corresponds to the unaffected hand in UCP and to the right hand in TD children, while the nondominant hand corresponds to the plegic hand in UCP and to the left hand in TD children.