Reorganization of the Action Observation Network and Sensory-Motor System in Children with Unilateral Cerebral Palsy: An fMRI Study

Table 3

Areas elicited by sensory-motor task for the dominant hand (DH) and nondominant hand (non-DH) in UCP children and in age-matched TD children.

		BA		UCP children					TD children
				Talairach’s coordinates			Cluster size	-value	Talairach’s coordinates			Cluster size	-value
				Motor-sensory task of DH	pSMC	2-3-4	CLH	−36	−27	53	8926	16.4	−40	−33	53	8811	17.9
ILH	37	−29	48				1794	6.1	42	−30	54	1046	5.0
IPL	40	CLH	−50		−29	26	1404	6.3	−50	−26	23	1212	5.5
		ILH	51		−24	25	1946	5.0	54	−20	22	931	6.0
PrC gyrus	6	CLH	−56		−3	29	1430	5.1	−57	−4	36	712	5.0
		ILH
Insula	13	CLH	−44		−11	16	663	6.2
		ILH
SMA	6–31	IH	−5		−17	48	1565	7.1	−4	−25	47	1024	6.9
Cerebellum		CLH
		ILH	14		−52	−23	1243	5.0	20	−52	−28	562	5.0
Motor-sensory task of non-DH	pSMC	2-3-4	CLH	35	−29	49	5928	10.1	38	−31	52	8645	18.3
			ILH	−41	−22	46	1032	7.5	−40	−25	55	621	5.8
	IPL	40	CLH	50	−20	27	1719	6.6	50	−25	22	1168	7.2
			ILH	−50	−29	25	502	5.1	−54	−30	28	1445	6.5
	PrC gyrus	6	CLH	48	3	31	878	5.3	42	−9	43	839	6.6
			ILH	−54	−5	29	554	5.7
	Insula	13	CLH	33	−24	17	613	5.6
			ILH	−46	−13	11	677	5.6
	SMA	6–31	IH	0	−12	47	988	5.0	1	−18	52	788	6.1
	Cerebellum		CLH
			ILH	−14	−52	−21	1495	7.3	−13	−61	−22	2288	7.0

BA = Brodmann area; UCP = unilateral cerebral palsy; TD = typically developing; pSMC = primary sensory-motor cortex; IPL = inferior parietal lobule; PrC gyrus = precentral gyrus; SMA = supplementary motor area; DH = dominant hand; non-DH = nondominant hand; CLH = contralateral hemisphere; ILH = ipsilateral hemisphere, IH = interhemispheric. For convention, the dominant hand corresponds to the unaffected hand in UCP and to the right hand in TD children, while the nondominant hand corresponds to the plegic hand in UCP and to the left hand in TD children.