Clinical Study

Changes in the Brain-Derived Neurotrophic Factor Are Associated with Improvements in Diabetes Risk Factors after Exercise Training in Adolescents with Obesity: The HEARTY Randomized Controlled Trial

Table 2

Relationship between changes in BDNF and changes in anthropometrics and diabetes risk factors in the exercise group.

MeasureCorrelation, value

Δ weight−0.0050.95
Δ waist circumference0.020.81
Δ BMI0.010.83
Δ %body fat−0.040.6
Δ glucose−0.170.04
Δ insulin0.130.1
Δ HbA1c0.010.89
Δ HOMA-B0.230.005
Δ HOMA-IS−0.060.46

Note: BMI = body mass index; HbA1c = hemoglobin A1c; HOMA-B = homeostatic model assessment beta cell secretory capacity; HOMA-IS = homeostatic model assessment insulin sensitivity.