Changes in the Brain-Derived Neurotrophic Factor Are Associated with Improvements in Diabetes Risk Factors after Exercise Training in Adolescents with Obesity: The HEARTY Randomized Controlled Trial
Table 3
Changes in diabetes risk factors predicting change in BDNF in the exercise group.
Effect
Beta estimate
value
Change in glucose
−6.565
3.374
0.054
Age
−0.176
1.028
0.864
Gender
2.240
3.105
0.472
Highest parental education
0.444
1.856
0.811
Change in BMI
0.185
0.716
0.797
Change in HOMA-B
0.093
0.031
0.004
Age
−0.551
1.031
0.594
Gender
3.802
3.129
0.226
Highest parental education
0.752
1.841
0.683
Change in BMI
−0.652
0.766
0.396
Change in HOMA-IS
−0.025
0.033
0.450
Age
−0.592
1.069
0.581
Gender
3.206
3.247
0.325
Highest parental education
0.785
1.895
0.679
Change in BMI
−0.133
0.787
0.866
Change in HbA1c (per 0.1%)
0.001
0.568
0.999
Age
−0.238
1.035
0.818
Gender
2.563
3.143
0.416
Highest parental education
0.650
1.882
0.730
Change in BMI
0.173
0.750
0.818
Change in insulin
0.049
0.027
0.076
Age
−0.643
1.048
0.540
Gender
3.478
3.209
0.280
Highest parental education
0.951
1.878
0.613
Change in BMI
−0.358
0.773
0.644
Note: BMI = body mass index; HbA1c = hemoglobin A1c; HOMA-B = homeostatic model assessment beta cell secretory capacity; HOMA-IS = homeostatic model assessment insulin sensitivity.
