Exposure to Patterned Auditory Stimuli during Acute Stress Prevents Despair-Like Behavior in Adult Mice That Were Previously Housed in an Enriched Environment in Combination with Auditory Stimuli

Figure 3

Effects of preexposure to standard conditions, environmental enrichment, patterned auditory stimuli, or environmental enrichment plus patterned auditory stimuli during housing and behavior in the forced-swim test. (a) Total time immobile, (b) immobile episodes, and (c) latency to the first immobile episode were analyzed. Data represent the mean ± standard error of the mean (SEM). Three-way ANOVA followed by the Student-Newman-Keuls test was performed, considering housing as factor A, presence of PAS during housing as factor B, and presence of PAS during FST as factor C. Asterisks in (a) indicate (), in (b) indicate (), and in (c) indicate () in ENR + PAS/FST + PAS compared with all other groups of mice. –8 per group.

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