Research Article

Chronic Unexpected Mild Stress Destroys Synaptic Plasticity of Neurons through a Glutamate Transporter, GLT-1, of Astrocytes in the Ischemic Stroke Rat

Figure 3

Ceftriaxone promoted newborn astrocytes in hippocampal DG in the CUMS-induced model rats transporting glutamate. (a) Representative immunofluorescent photomicrographs (200×) of glutamate (Glu, green) in newborn astrocytes (GFAP/BrdU, red/blue) were pictured on the 21st/28th/42nd day. Scale bars: 20 μm. (b) Representative immunofluorescent photomicrographs (200×) of glutamine (Gln, green) in newborn astrocytes (GFAP/BrdU, red/blue) on the 21st/28th/42nd day. Scale bars: 20 μm. (c) Fluorescence intensity of glutamate in newborn astrocytes was modulated by astroglial GLT-1. (d) Trend of glutamine intensity was paralleled with glutamate in newborn astrocytes in hippocampal DG. , , , , two-way ANOVA (Tukey), .
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