Morphological Neuroimaging Biomarkers for Tinnitus: Evidence Obtained by Applying Machine Learning

Table 2

Volumetric structures used in SVM classification model.

Brain region	Peak MNI ()	References
Right hemisphere
Ventromedial prefrontal cortex	2, 21, -15	Leaver et al. [21]
Dorsomedial prefrontal cortex	2, 38, 39
Superior temporal gyrus	52, -41, 13	Boyen et al. [5]
	51, -4, -2	Aldhafeeri et al. [20]
	46, -15, -6	Schecklmann et al. [8]
	51, -6, -9
	59, -1, -4	Meyer et al. [4]
Cingulate gyrus	4, 49, -5	Aldhafeeri et al. [20]
	10, 30, 22
	5, -55, 28
Middle temporal gyrus	48, -58, 6; 63, 5, -17	Aldhafeeri et al. [20]
	49, -70, 13	Boyen et al. [5]
	46, -15, -6; 51, -6, -9	Schecklmann et al. [8]
Parahippocampal gyrus	14, 5, -17	Aldhafeeri et al. [20]
	37, -35, -15	Meyer et al. [4]
Inferior temporal gyrus	47, -32, -17	Aldhafeeri et al. [20]
	55, -23, -24	Meyer et al. [4]
Rostral middle frontal gyrus	37, 51, 9	Meyer et al. [4]
	16, 21, -17
Inferior parietal lobule	44, -63, 39	Meyer et al. [4]
	43, -66, 25
	46, -56, 44
Insula	36, 3, 1	Meyer et al. [4]
	39, 1, 1
Superior temporal gyrus (primary auditory cortex, BA41)	43, -30, 10	Aldhafeeri et al. [20]
Cuneus	5, -77, 16	Meyer et al. [4]
Transverse temporal gyrus	43, -24, 3
Pars orbitalis	45, -55, 43
Supramarginal gyrus	59, -40, 24	Leaver et al. [21]
	57, -57, 27	Boyen et al. [5]
Occipital lobe	1, -84, -3
Hypothalamus	5, -5, -11
Superior frontal gyrus	11, 18, 59	Aldhafeeri et al. [20]
Middle frontal gyrus	48, 35, 20
Inferior frontal gyrus	50, 19, -12
Left hemisphere
Superior temporal gyrus	-46, -34, 10	Boyen et al. [5]
	-63, -6, 1	Aldhafeeri et al. [20]
	-44, -12, -11	Schecklmann et al. [8]
	-58, -16, 6
	-48, 9, -25	Meyer et al. [4]
	-47, 8, -26
Cingulate gyrus	-14, 23, -13	Aldhafeeri et al. [20]
	-20, 5, 43
	-4, -43, 29
Middle temporal gyrus	-44, -12, -11	Schecklmann et al. [8]
Parahippocampal gyrus	-20, 2, -23	Aldhafeeri et al. [20]
Inferior temporal gyrus	-62, -12, -26	Aldhafeeri et al. [20]
	-44, -50, -12	Meyer et al. [4]
	-45, -50, -12
Rostral middle frontal gyrus	-20, 56, -2	Meyer et al. [4]
	-23, 54, 16
	-20, 55, -3
Superior frontal gyrus	-7, 27, 55	Meyer et al. [4]
	-7, 52, 36
	-11, 63, 19	Boyen et al. [5]
	-12, 65, 6	Aldhafeeri et al. [20]
Superior temporal gyrus (primary auditory cortex, BA41)	-42, -23, 10	Aldhafeeri et al. [20]
Transverse temporal gyrus	-51, -21, 4	Meyer et al. [4]
Hypothalamus	-4, -10, -6	Boyen et al. [5]
Middle frontal gyrus	-36, 35, 28	Aldhafeeri et al. [20]
Inferior frontal gyrus	-10, 63, 8
Postcentral gyrus	-32, -31, 61	Meyer et al. [4]

MNI: Montreal Neurological Institute.