Novelty and Novel Objects Increase c-Fos Immunoreactivity in Mossy Cells in the Mouse Dentate Gyrus

Figure 6

Hilar c-fos labeling is weak in mice exposed to familiar objects compared to novel objects and very strong when mice had not been previously exposed to objects. Three sections are shown with insets showing more detail. The sections are from comparable dorsoventral levels. Mice were either exposed to familiar objects (a) or novel objects (b) or had not been exposed previously to objects (c). Arrows point to c-fos ir hilar cells. Calibrations: 100 μm. MOL=molecular layer.

(a)

(b)

(c)