Research Article
Alterations of the Brain Microstructure and Corresponding Functional Connectivity in Early-Blind Adolescents
Table 1
Clinical characteristics of early-blind adolescents and normal-sighted controls.
| | No. | Age (years) | Gender | Age of onset (months) | Causes of blindness |
| | LP01 | 11.8 | M | 2 | ROP | | LP02 | 14.7 | M | 2 | Cataract | | LP03 | 14.4 | M | 0 | CG; EA | | LP04 | 11.0 | M | 0 | CRL | | LP05 | 12.3 | M | 3 | ROP | | LP06 | 12.5 | F | 8 | ROP | | LP07 | 13.8 | M | 0 | CRL | | LP08 | 15.0 | F | 0 | CRL | | NLP01 | 14.3 | M | 3 | ROP | | NLP02 | 16.3 | M | 2 | ROP | | NLP03 | 17.2 | M | 8 | OT | | NLP04 | 11.0 | M | 0 | ROP | | NLP05 | 13.8 | F | 1 | ROP; EA | | NLP06 | 17.9 | F | 5 | Cataract; EA | | NLP07 | 12.3 | F | 3 | ROP | | NLP08 | 17.1 | F | 0 | ROP; OA | | NLP09 | 17.8 | M | 0 | ROP | | NLP10 | 14.5 | F | 1 | ROP | | NLP11 | 14.8 | M | 4 | ROP | | NLP12 | 14.9 | M | 0 | CRL | | NLP13 | 11.1 | F | 3 | ET; EE | | NLP14 | 13.2 | M | 0 | CRL | | NLP15 | 13.7 | F | 0 | ROP | | NSC01 | 12.5 | F | — | — | | NSC02 | 12.0 | M | — | — | | NSC03 | 14.0 | M | — | — | | NSC04 | 17.2 | M | — | — | | NSC05 | 13.6 | M | — | — | | NSC06 | 12.5 | M | — | — | | NSC07 | 13.3 | M | — | — | | NSC08 | 18.3 | F | — | — | | NSC09 | 12.1 | M | — | — | | NSC10 | 18.2 | F | — | — | | NSC11 | 15.5 | M | — | — | | NSC12 | 16.5 | M | — | — | | NSC13 | 13.9 | M | — | — | | NSC14 | 18.7 | F | — | — | | NSC15 | 17.6 | F | — | — | | NSC16 | 17.0 | F | — | — | | NSC17 | 15.4 | F | — | — | | NSC18 | 15.0 | F | — | — | | NSC19 | 11.0 | F | — | — | | NSC20 | 15.0 | F | — | — | | NSC21 | 13.0 | F | — | — |
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Abbreviations: LP: early-blind adolescents with light perception; NLP: early-blind adolescents without light perception; NSC: normal-sighted controls; M: male; F: female; ROP: retinopathy of prematurity; OT: oxygen toxicity; EA: eyeball atrophy; CRL: congenital retinal lesions: CG, congenital glaucoma; OA: optic atrophy; ET: eyeball tumor; and EE: eyeball extraction.
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