Alterations of the Brain Microstructure and Corresponding Functional Connectivity in Early-Blind Adolescents

Table 4

Brain regions with significant changes of RSFC between groups.

Between-group comparison	ROI seeds	Brain regions	Abbreviations	Cluster size (voxels)	score	Peak MNI
						NLPs vs. NSC	OG.L	Left inferior frontal gyrus, triangular part	IFGtri.L	77	5.12	-39	33	6
Right inferior frontal gyrus, opercular part	IFGoper.R	115	6.77	57	21			33
Left middle frontal gyrus	MFG.L	97	5.68	-45	18			18
ParaHIP.R	Left superior frontal gyrus	SFG.L	67	5.96	67		-24	30
SOG.R	Left fusiform gyrus	FG.L	188	-5.93	-24		-66	-15
	Right supramarginal gyrus	SMG.R	62	5.16	60		-33	39
	Left superior frontal gyrus	SFG.L	48	4.63	24		-93	6
LPs vs. NSC	MOG.L	Right middle occipital gyrus	MOG.R	47	-5.15	24	-93	6

The results were corrected by the AlphaSim method at a voxel level of . Abbreviations: RSFC: resting-state functional connectivity; ROI: region of interest; OG.L: left occipital gyrus; ParaHIP.R: right parahippocampal gyrus; SOG.R: right superior occipital gyrus; MOG.L; left middle occipital gyrus; LP: early-blind adolescents with residual light perception; NLP; early-blind adolescents without light perception; NSC: normal-sighted controls; MNI: Montreal Neurological Institute.