MZF1 in the Dorsal Root Ganglia Contributes to the Development and Maintenance of Neuropathic Pain via Regulation of TRPV1

Figure 3

TRPV1 immunoreactivity (IR) in DRGs increases after CCI. (a, b) Representative images showing TRPV1 IR in DRGs for sham-surgery control (a) and at 7 days post-CCI (b). Scale bar for (a) and (b): 100 μm. (c) Quantification of TRPV1-positive area in DRGs. vs. the sham group Student’s -test. (d–l) Double-labeled immunofluorescent images showing the TRPV1 (red: (e), (h), and (k)) colocalized with NF200 (green: (d)) and IB4 (green: (g)), but not GFAP (green: (j)). The pairs of images are merged in (f), (i), and (l). Scale bar for (d)–(l): 50 μm.

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