MMP-9 Contributes to Dendritic Spine Remodeling Following Traumatic Brain Injury

Figure 5

Effects of MMP-9 on spine shape changes in the dentate gyrus of animals 1 week post-CCI. (a) Head width calculated in the ipsi- and contralateral hippocampus of C57Bl6/J mice, 7 days after CCI and sham procedures. (b) Length/width ratio calculated in the ipsi- and contralateral hippocampus of C57Bl6/J mice, 7 days after CCI and sham-operated animals. (c) Dendrite pictures from the ipsi- and contralateral dentate gyrus and sham animals. (d) Representative dendrite pictures from the ipsi- and contralateral dentate gyrus and sham animals. Data are presented as . Statistical analysis was carried out using one-way ANOVA followed by Tukey’s post hoc test. Asterisk indicate statistical significance from the CCI and sham groups, respectively. ; .

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