Role of Functional Imaging Techniques to Assess Motor and Language Cortical Plasticity in Glioma Patients: A Systematic Review

Figure 4

Schematic representation of the major mechanisms of functional reorganization of motor function in the subacute phase of a stroke lesion and postoperatively in a tumor lesion. Functional MRI activations of primary and secondary motor areas during the subacute phase of a stroke lesion (green color) and postoperatively in a low-grade glioma (LGG) (blue color) in the left precentral region. Comparison of two models of reorganization shows a similar pattern of motor-activated areas, but an overactivation of ipsilesional and contralesional areas (M1, premotor area, and supplementary motor area) is evident in ischemic lesion compared to LGG.