Memantine Differentially Regulates Tau Phosphorylation Induced by Chronic Restraint Stress of Varying Duration in Mice

Figure 8

The effect of memantine on the expression of chaperone proteins in mice following 28 consecutive days of chronic restraint stress (CRS). (a) Frontal cortex lysates from the four groups were immunoblotted with antibodies against Pin1 and heat shock proteins HSP70, HSC70, and HSP90. (b) Densitometric quantification of the bands in (a). The results are shown as means ± SEM ( in each group); β-actin was used as a loading control. . Con: control.

(a)

(b)