Research Article

Neuromodulatory Effects of Transcranial Direct Current Stimulation on Motor Excitability in Rats

Figure 2

Effect of tDCS on MEPs in rats. (a) Time course changes of MEPs following sham, tDCS (+, 0.1 mA), tDCS (+, 0.8 mA), tDCS (-, 0.1 mA), and tDCS (-, 0.8 mA) interventions. Representative MEP traces following tDCS present no obvious change after sham stimulation, whereas traces of an increase in MEP amplitude after tDCS (+, 0.1 mA or 0.8 mA) and a reduction in MEP amplitude after tDCS (-, 0.8 mA) are observed. (b) Averaged changes in the MEP amplitude after sham, low-intensity anodal tDCS (0.1 mA), high-intensity anodal tDCS (0.8 mA), low-intensity cathodal tDCS (0.1 mA), and high-intensity cathodal tDCS (0.8 mA) are presented. Asterisks () indicate a significant difference when compared with the sham group at the same time point (unpaired -test). , , , .
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