Epigenetic Modulation on Tau Phosphorylation in Alzheimer’s Disease

Figure 2

Epigenetic modulation on tau phosphorylation and possible impacts on synapses and neurons. Dysregulated epigenetic modification on genes associated with the tau phosphorylation process could lead to NFT aggregation which can then cause neuroinflammation, axonal transport dysfunction, and mitochondrial and synaptic plasticity injuries.