Ganglionic Long-Term Potentiation in Prehypertensive and Hypertensive Stages of Spontaneously Hypertensive Rats Depends on GABA Modulation
LTP of normal amplitude was expressed in SCG from both SHR and WKy rats at an intermediate age (8 wo). (a) Time course of synaptic potentiation, expressed as (), and recorded in ganglia isolated from SHR (black circles: ) and WKy (white circles: ) at 8 wo. (b) Bar plots of LTP parameters showing that both SCG from SHR and WKy expressed LTP with values within the ranges of LTP control (LTP decay of and LTP extent of for SHR and LTP decay of and LTP extent of for WKy; for both LTP decay and LTP extent). Dotted line in (a) indicates the LTP baseline (0.2).
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